Premarin Tablets (0.3mg, 0.625mg, & 1.25mg)

Premarin is a hormone replacement therapy (HRT) that is used to treat the symptoms of menopause; the stage of significant hormonal changes in the female body, as hormone levels drop and the menstrual cycle ends. It contains active ingredients of conjugated oestrogens, which are a substitute for oestrogen, the major female sex hormone. These ingredients include estrone, equilin, 17a-estradiol and 17b-estradiol.

You may be prescribed Premarin in 0.3 mg, 0.625 mg or 1.25 mg strengths, with your dose being adjusted according to factors such as the severity of symptoms and risk of side effects.

Premarin tablets are used to relieve menopause symptoms such as night sweats, hot flushes and vaginal dryness. HRT treatments such as Premarin work by supplementing your hormone levels, which have fallen during menopause. The conjugated oestrogens in Premarin not only replace lost oestrogen and treat menopause symptoms, but they can also help to prevent postmenopausal osteoporosis.

If your womb hasn’t been removed, you will require a treatment containing progesterone to take with your Premarin. This is to ensure that the lining of your womb (endometrium) doesn’t grow excessively, as this reduces the risk of endometrial cancer and other complications.

You shouldn’t smoke or use tobacco products whilst taking Premarin tablets. Smoking while taking Premarin can increase the risk of serious side effects including serious cardiovascular events, such as:

• Blood clots
• Deep vein thrombosis
• Pulmonary embolism
• Stroke
• Heart attack

If you experience any side effects related to these conditions – such as:

• Pain or an uncomfortable pressure in your chest
• Pain or discomfort in your back, arms, jaw, neck or stomach
• Shortness of breath

It is imperative that you seek medical attention or call 999 as soon as possible.

Grapefruit juice and foods containing grapefruit can increase the side effects of oestrogen – including breast pain or tenderness, nausea, fluid retention and headache - in some women. As the clinical significance of this interaction is unknown, you don’t need to limit your grapefruit consumption, but if you do notice any unusual side effects, report them to your doctor.

Like Premarin, Cenestin is an HRT treatment that is used to treat menopausal symptoms, as well as atrophic vaginitis. Unlike Premarin, Cenestin is not taken to prevent osteoporosis or treat primary ovarian failure. Although the two treatments both contain conjugated oestrogens, they include different active ingredients. Cenestin contains a combination of nine active ingredients – like Premarin, it contains equilin, 17a-estradiol and 17b-estradiol, and other active ingredients including 17a-dihydroequilin, 17b-dihydroequilin, 17a-dihydroequilin, 17b-dihydroequilenin and equilenin.

Cenestin tablets and Premarin tablets are both taken once per day, and come in 0.625 mg and 1.25 mg strengths. While Cenestin is also prescribed in 0.45 mg and 0.9 mg strength tablets, Premarin is also available in a 0.3 mg strength. Cenestin and Premarin share many of the same potential side effects, including nausea, vomiting, stomach pain, bloating, breast tenderness, breast pain, weight changes and headache.

Prempro and Premarin are both HRT treatments, but along with the conjugated oestrogens (the active ingredients of Premarin) Prempro also contains medroxyprogesterone, a type of progestin (the female sex hormone) that protects the uterus (womb) from damage, helping to prevent uterine cancer. Prempro and Premarin can both also be used to prevent osteoporosis.

If your uterus is intact, you may be given a combined HRT treatment such as Prempro to replace the oestrogen you have lost during menopause, reducing symptoms such as hot flushes, night sweats and vaginal dryness. The medroxyprogesterone contained in the tablets can help to prevent the thickening of your uterus lining (endometrial hyperplasia) that can be caused by taking conjugated oestrogens.

Prempro comes in a wider range of strengths than Premarin, including: a cream tablet containing 0.3 mg conjugated oestrogens and 1.5 mg medroxyprogesterone, a gold tablet containing 0.45 mg conjugated oestrogens and 1.5 mg medroxyprogesterone, a peach tablet containing 0.625 mg conjugated oestrogens and 2.5 mg medroxyprogesterone, and a light blue tablet containing 0.625 mg conjugated oestrogens and 5 mg medroxyprogesterone. Prempro and Premarin are both taken once per day.

Some users have reported that Premarin was successful in reducing menopausal symptoms such as hot flushes, night sweats, mood swings and loss of libido (sex drive) in a matter of days or weeks. Reviewers online have expressed their happiness that Premarin helped them regain their interest in sex and get their sex life back. However, some users who stopped Premarin reported that their symptoms returned and that they had trouble sleeping.

You can’t purchase Premarin tablets over the counter in the UK. A doctor will need to assess your suitability for the treatment before you can be issued a prescription. Once your suitability has been confirmed, you can use your prescription to purchase Premarin tablets from your local or online pharmacy.

Premarin tablets can be bought online at Cloud Pharmacy. After completing a quick consultation with an online pharmacist, we can then issue you an electronic prescription. Once your prescription has been issued, we can dispense the tablets and send them to you in a discreet package with our next day delivery service.